Publications

Fehsenfeld S., Quijada-Rodriquez A.R., Zhouyao H., Durant A.C., Donini A., Sachs M., Eck P., Weihrauch D. 2023. Hiat1 as a new transporter involved in ammonia regulation. Scientific Reports 13, Article number 4416. Article

Picinic B., Durant, A., Donini A. 2022 Effect of salt and brine-beet juice de-icer on osmoregulatory physiology of the freshwater amphipod Hyalella azteca (Saussure, 1858) (Amphipoda: Hyalellidae). Journal of Crustacean Biology 42 (2) Article

Silver S., Donini A. 2021 Physiological responses of freshwater insects to salinity: molecular, cellular and organ level studies. Journal of Experimental Biology 224 (20) Article

Durant A.C., Grieco Guardian E., Kolosov D., Donini A. 2021 The transcriptome of anal papillae of Aedes aegypti reveals their importance in xenobiotic detoxification and adds significant knowledge on ion, water and ammonia transport mechanisms. Journal of Insect Physiology 132, 104269 Article

Durant A.C., Donini A. 2020 Ammonium transporter expression in sperm of the disease-vector Aedes aegypti mosquito influences male fertility. PNAS Article

Lajevardi A., Sajadi F., Donini A., Paluzzi J-P. V. 2020 Studying the activity of neuropeptides and other regulators of the excretory system in the adult mosquito. JoVE (In Press)

Misyura L., Grieco Guardian E., Durant A.C., Donini A. 2020 A comparison of aquaporin expression in mosquito larvae (Aedes aegypti) that develop in hypo-osmotic freshwater and iso-osmotic brackish water. PLoS ONE 15(8): e0234892 Article

Durant A.C., Donini A. 2019 Development of Aedes aegypti (Diptera, Culicidae) mosquito larvae in high ammonia sewage in septic tanks causes alterations in ammonia excretion, ammonia transporter expression, and osmoregulation. Scientific Reports 9; 19028 (2019) Article

Jass A., Yerushalmi G.Y., Davis H.E., Donini A., MacMillan H.A. 2019 An impressive capacity for cold tolerance plasticity protects against ionoregulatory collapse in the disease vector Aedes aegypti. Journal of Experimental Biology (In Press)

Livingston D.B.H., Patel H., Donini A., MacMillan H.A. 2019 Active transport of brilliant blue FCF across the Drosophila midgut and Malpighian tubule epithelia. Comparative Biochemistry and Physiology A: Molecular and Integrative Physiology (In Press)

Kolosov D., Jonusaite S., Donini A., Kelly S.P., O’Donnell M.J. 2019 Septate junction in the distal ileac plexus of larval lepidopteran Trichoplusia ni: alterations in paracellular permeability during ion transport reversal. Journal of Experimental Biology Article

Nowghani F., Chen C.C., Jonusaite S., Watson-Leung T., Kelly S.P., Donini A. 2019 Impact of salt-contaminated freshwater on osmoregulation and tracheal gill function in nymphs of the mayfly Hexagenia rigida. Aquatic Toxicology Article

Durant A.C., Donini A. 2018 Evidence that Rh proteins in the anal papillae of the freshwater mosquito Aedes aegypti are involved in the regulation of acid base balance in elevated salt and ammonia environments. Journal of Experimental Biology Article

MacMillan H.A., Nazal B., Wali S., Yerushalmi G.Y., Misyura L., Donini A., Paluzzi J-P. 2018 Anti-diuretic activity of a CAPA neuropeptide can compromise Drosophila chill tolerance. Journal of Experimental Biology 221 (19) Article

Kolosov D., Tauqir M., Rajaruban S., Piermarini P.M., Donini A., O’Donnell M.J. 2018 Molecular mechanisms of bi-directional ion transport in the Malpighian tubules of a lepidopteran crop pest, Trichoplusia ni. Journal of Insect Physiology 109: 55-68

Tachie-Mensah E., Blanco A.M., Donini A., Unniappan S. 2018 Galanin decreases spontaneous resting contractions and potentiates acetyl choline-induced contractions of goldfish gut. Neuropeptides 69: 92-97

Durant A.C., Donini A. 2018 Ammonia excretion in an osmoregulatory syncytium is facilitated by AeAmt2, a novel ammonia transporter in Aedes aegypti larvae. Frontiers in Physiology, Invertebrate Physiology March 20, 2018. Article

Durant A.C., Celis-Salgado M.P., Ezatollahpour S., Yan N.D., Arnott S.E., Donini A. 2018 Ca2+ levels in Daphnia hemolymph may explain occurrences of daphniid species along recent Ca gradients in Canadian soft-water lakes. Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology 218:8-15. Article

Yerushalmi G., Misyura L., MacMillan H. A., Donini A. 2018 Functional plasticity of the gut and the Malpighian tubules underlies cold acclimation and mitigates cold-induced hyperkalemia in Drosophila melanogaster Journal of Experimental Biology Article

Des Marteaux, L.E., Khazraeenia, S., Yerushalmi, G.Y., Donini, A., Li, N.G., Sinclair, B.J. 2018 The effect of cold acclimation on active ion transport in cricket ionoregulatory tissues. Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology 216:28-33. Article

Nowghani F., Jonusaite S., Watson-Leung T., Donini A., Kelly S.P. 2017 Strategies of ionoregulation in the freshwater nymph of the mayfly (Hexagenia rigida). Journal of Experimental Biology 220:3997-4006. [Article Hi-lighted on Cover of Issue] Article

MacMillan H.A., Yerushalmi, G., Jonusaite, S., Kelly, S.P., Donini, A. 2017 Thermal acclimation mitigates paracellular leak from the Drosophila gut. Scientific Reports 7 Article 8807. Article

Misyura, L., Yerushalmi, G., Donini, A. 2017 A mosquito entomoglyceroporin, Aedes aegypti AQP5 participates in water transport across the Malpighian tubules of larvae. Journal of Experimental Biology 220:3536-3544. Article

Jonusaite, S., Kelly, S.P., Donini, A. 2017 Identification of the septate junction protein gliotactin in the mosquito, Aedes aegypti: evidence for a role in increased paracellular permeability in larvae. Journal of Experimental Biology 220:2354-2363. Article

Durant, A.C., Chasiotis, H., Misyura, L., Donini, A. 2017 Aedes aegypti Rhesus glycoproteins contribute to ammonia excretion by larval anal papillae. Journal of Experimental Biology 220:588-596. Article

Jonusaite, S., Donini, A., Kelly, S.P. 2017 Salinity alters snakeskin and mesh transcript abundance and permeability in midgut and Malpighian tubules of larval mosquito, Aedes aegypti Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology 205: 58-67. Article

Akhter, H., Misyura, L., Bui, P., Donini, A. 2017 Salinity responsive aquaporins in the anal papillae of the larval mosquito, Aedes aegypti. Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology 203:144-151 Article

Andersen, M.K., MacMillan, H.A., Donini, A., Overgaard, J. 2017 Cold tolerance of Drosophila species is tightly linked to epithelial K+ transport capacity of the Malpighian tubules and rectal pads. Journal of Experimental Biology Accepted Sept 19, 2017Article

Kolosov, D., Bui, P., Donini, A., Wilkie, M., Kelly, S.P. 2017 A role for tight junction-associated MARVEL proteins in larval sea lamprey (Petromyzon marinus) osmoregulation. Journal of Experimental Biology 220:3657-3670. Article

Platek, A., Turko, A., Donini, A., Kelly, S.P., Wright, P. 2017 Environmental calcium regulates gill remodeling in an euryhaline teleost fish. Journal of Experimental Zoology Part A. In Press

D’Silva, N.M., Donini, A., O’Donnell, M.J. 2017 The roles of V-type H+-ATPase and Na+/K+-ATPase in energizing K+ and H+ transport in larval Drosophila gut epithelium. Journal of Insect Physiology 98: 284-290. Article

Tachie-Mensah, E., Blanco, A. M., Donini, A., Unniappan, S. 2017 Brain and intestinal expression of Galanin-like peptide (GALP), Galanin receptor R1 and Galanin receptor R2, and GALP regulation of food intake in goldfish (Carassius auratus). Neuroscience Letters 637: 126-135. Article

Kolosov, D., Donini, A., Kelly, S.P. 2017 Claudin-31 contributes to corticosteroid-induced alterations in the barrier properties of the gill epithelium. Molecular and Cellular Endocrinology 439: 457-466.

Yerushalmi, G., Misyura, L., Donini, A., MacMillan, H.A. 2016 Chronic dietary salt stress mitigates hyperkalemia and facilitates chill coma recovery in Drosophila melanogaster. Journal of Insect Physiology 95:89-97 Article

Zadeh Tahmasebi, M., Bui, P., Donini, A. 2016 Fluid and ion secretion by Malpighian tubules of larval chironomids, Chironomus riparius: Effects of rearing salinity, transport inhibitors and serotonin. Archives of Insect Biochemistry and Physiology 93:67-85 Article

Jonusaite, S., Kelly, S.P., Donini, A. 2016 The response of claudin-like transmembrane septate junction proteins to altered environmental ion levels in the larval mosquito Aedes aegypti. Journal of Comparative Physiology B, Biochemical, Systemic and Environmental Physiology 186:589-602 Article

Chasiotis, H., Ionescu, A., Misyura, L., Bui, P., Fazio, K., Wang, J., Patrick, M., Weihrauch, D., Donini, A. 2016 An animal homolog of plant Mep/Amt transporters promotes ammonia excretion by the anal papillae of the disease vector mosquito, Aedes aegypti. Journal of Experimental Biology 219: 1346-1355 doi: 10.1242/jeb.134494. Article

Jonusaite, S., Donini, A., Kelly, S.P. 2016 Occluding junctions of invertebrate epithelia. Journal of Comparative Physiology B, Biochemical, Systemic and Environmental Physiology 186(1): 17-43. Article

Ruiz-Sanchez, E., O’Donnell, M.J., Donini, A. 2015. Secretion of Na+, K+ and fluid by the Malpighian (renal) tubule of the larval cabbage looper Tichoplusia ni (Lepidoptera Noctuidae). Journal of Insect Physiology 82: 92-98.

MacMillan, H.A., Ferguson, L.V., Nicolai, A., Donini, A., Staples, J.F., Sinclair, B.J. 2015. Parallel ionoregulatory adjustments underlie phenotypic plasticity and evolution of Drosophila cold tolerance. Journal of Experimental Biology 218: 423-432.

Robertson, L., Chasiotis, H., Galperin, V., Donini, A. 2014. Allatostatin A-like immunoreactivity in the nervous system and gut of the larval midge, Chironomus riparius (Meigen): Modulation of hindgut motility, rectal K+ transport and implications for exposure to salinity. Journal of Experimental Biology 217: 3815-3822.

Robertson, L., Donini, A., Lange, A.B. 2014. K+ absorption by locust gut and inhibition of ileal K+ and water transport by FGLamide allatostatins. Journal of Experimental Biology 217: 3377-3385.

Jonusaite, S., Kelly, S.P., Donini, A. 2013. Tissue specific ionomotive enzyme activity and K+ reabsorption reveal the rectum as an important ionoregulatory organ in larval Chironomous riparius exposed to varying salinity. Journal of Experimental Biology 216: 3637-3648.

Ionescu, A., Donini, A. 2012. AedesCAPA-PVK-1 displays diuretic and dose dependent antidiuretic potential in the larval mosquito Aedes aegypti (Liverpool). Journal of Insect Physiology 58(10):1299-1306.

Marusalin, J., Matier, B., Rheault, M.R., Donini, A. 2012. Aquaporin homologs and water transport in the anal papillae of the larval mosquito, Aedes aegypti. Journal of Comparative Physiology B, Biochemical, Systemic and Environmental Physiology 182 (8): 1047-1056.

Weihrauch, D., Donini, A., O’Donnell, M.J. 2012. Ammonia transport by terrestrial and aquatic insects. Journal of Insect Physiology 58(4):473-487.

Del Duca, O., Nasirian, A., Galperin, V., Donini, A. 2011. Pharmacological characterisation of apical Na+ and Cl- transport mechanisms of the anal papillae in the larval mosquito Aedes aegypti. Journal of Experimental Biology 214 (23):3992-3999.

Jonusaite, S., Kelly, S.P., Donini, A. 2011. The physiological response of larval Chironomus riparius (Meigen) to abrupt brackish water exposure. Journal of Comparative Physiology B, Biochemical, Systemic and Environmental Physiology 181 (3):343-352.

Nguyen, H., Donini, A. 2010. Larvae of the midge, Chironomus riparius possess two distinct mechanisms for ionoregulation in response to ion-poor conditions. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 299: R762-773.

Galvez, F., Donini, A., Playle, R.C., Smith, S., O’Donnell, M.J., Wood, C.M. 2008. A matter of potential concern: Natural organic matter alters the electrical properties of fish gills. Environmental Science and Technology 42 (24): 9385 – 9390.

Orchard I., Donini, A. 2008. Aspects of the control of diuresis in the blood gorging insect, Rhodnius prolixus. Pestycydy 1-2: 61-66.

Donini, A., O’Donnell M.J., Orchard I. 2008. Differential actions of diuretic factors on the Malpighian tubules of Rhodnius prolixus. Journal of Experimental Biology 211 (1): 42-48.

Donini, A., Gaidhu, M.P., Strasberg, D., O’Donnell M.J. 2007. Changing salinity induces alterations in hemolymph ion concentrations and Na+ and Cl- transport kinetics of the anal papillae in the larval mosquito, Aedes aegypti. Journal of Experimental Biology 210: 983-992.

Donini, A., Patrick, M.L., Bijelic, G., Christensen, R.J., Ianowski, J.P., Rheault, M.R., O’Donnell, M.J. 2006. Secretion of water and ions by Malpighian tubules of larval mosquitoes: effects of diuretic factors, second messengers and salinity. Physiological and Biochemical Zoology 79(3): 645-655.

Donini, A., Patrick, M.L., O’Donnell, M.J. 2006. Rapid regulation of ion transport by Malpighian tubules and anal papillae of mosquito larvae in response to changing salinity. The Physiologist 49(6), C1-26. Invited speaker.

Donini, A., O’Donnell, M.J. 2005. Analysis of Na+, Cl-, K+, H+ and NH4+ concentration gradients adjacent to the surface of anal papillae of the mosquito Aedes aegypti: application of self-referencing ion-selective microelectrodes. Journal of Experimental Biology 208: 603-610.

Donini, A., Lange, A.B. 2004. Evidence for a possible neurotransmitter/neuromodulator role of tyramine on the locust oviducts. Journal of Insect Physiology 50 (4): 351-361.

Donini, A., Ngo, C., Lange, A.B. 2002. Evidence for crustacean cardioactive peptide-like innervation of the gut in Locusta migratoria. Peptides 23 (11): 1915-1923.

Donini, A., Lange, A.B. 2002. The effects of crustacean cardioactive peptide on locust oviducts are calcium-dependent. Peptides, 23 (4): 683-691.

Donini, A., Agricola, H-J., Lange, A.B. 2001. Crustacean cardioactive peptide is a modulator of oviduct contractions in Locusta migratoria. Journal of Insect Physiology 47 (3): 277-285.

Lange, A.B.; Donini, A. The involvement of crustacean cardioactive peptide (CCAP) in the control of oviduct muscle of Locusta. In: Goos, H.J. Th.; Rastogi, R.K.; Vaudry, H.; Pierantoni, R. Editors. Perspective in Comparative Endocrinology: Unity and Diversity. Bologna, Italy: Monduzzi Editore Spa; 2001: 899-903.